CDK6 antibody
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- Target See all CDK6 Antibodies
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CDK6
- Isotype
- IgG
- Top Product
- Discover our top product CDK6 Primary Antibody
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- Application Notes
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C/-80 °C
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- Target
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
- Alternative Name
- CDK6 (CDK6 Products)
- Synonyms
- CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
- Background
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The cyclin-dependent kinases form complexes with their cyclin partners and with CDK inhibitors. CDK6 and CDK4 associate with the D-type cyclins and target the retinoblastoma protein, allowing passage through the G1/S phase restriction point. CDK6/cyclin D complexes are sequestered in their inactive form through binding to one of the INK4 CDK inhibitor family members. Unlike the INK4 family of cdk inhibitors, the CDK inhibitor p21 Waf1/Cip1 may enhance the association of CDK4 and CDK6 with their cyclin D partners.
Synonyms: MGC59692, PLSTIRE - Gene ID
- 1021
- UniProt
- Q00534
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
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