TLR8 antibody (AA 849-1041)

Catalog No. ABIN3022015

Product Details anti-TLR8 Antibody

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Binding Specificity: AA 849-1041

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: HHLFYWDVWF IYNVCLAKVK GYRSLSTSQT FYDAYISYDT KDASVTDWVI NELRYHLEES RDKNVLLCLE ERDWDPGLAI IDNLMQSINQ SKKTVFVLTK KYAKSWNFKT AFYLALQRLM DENMDVIIFI LLEPVLQHSQ YLRLRQRICK SSILQWPDNP KAEGLFWQTL RNVVLTENDS RYNNMYVDSI KQY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 849-1041 of human TLR8 (NP_619542.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Alternative Name: TLR8 (TLR8 Products)

Synonyms: CD288 antibody, toll like receptor 8 antibody, toll-like receptor 8 antibody, TLR8 antibody, Tlr8 antibody

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.,TLR8,CD288,TLR8,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR8

Molecular Weight: 119 kDa/121 kDa

Gene ID: 51311

UniProt: Q9NR97

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades