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Fibrinogen beta Chain antibody (AA 202-491)
FGB
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Fibrinogen beta Chain Antibody
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Target
See all Fibrinogen beta Chain (FGB) Antibodies
Fibrinogen beta Chain (FGB)
Binding Specificity
All epitopes for Fibrinogen beta Chain antibodies
AA 202-491
Reactivity
All reactivities for Fibrinogen beta Chain antibodies
Human
Host
All hosts for Fibrinogen beta Chain antibodies
Rabbit
Clonality
All clonalities for Fibrinogen beta Chain antibodies
Polyclonal
Conjugate
All conjugates for Fibrinogen beta Chain antibodies
This Fibrinogen beta Chain antibody is un-conjugated
Application
All applications for Fibrinogen beta Chain antibodies
Western Blotting (WB)
Sequence
LENLRSKIQK LESDVSAQME YCRTPCTVSC NIPVVSGKEC EEIIRKGGET SEMYLIQPDS SVKPYRVYCD MNTENGGWTV IQNRQDGSVD FGRKWDPYKQ GFGNVATNTD GKNYCGLPGE YWLGNDKISQ LTRMGPTELL IEMEDWKGDK VKAHYGGFTV QNEANKYQIS VNKYRGTAGN ALMDGASQLM GENRTMTIHN GMFFSTYDRD NDGWLTSDPR KQCSKEDGGG WWYNRCHAAN PNGRYYWGGQ YTWDMAKHGT DDGVVWMNWK GSWYSMRKMS MKIRPFFPQQ
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Fibrinogen beta Chain
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Target
Fibrinogen beta Chain (FGB)
Alternative Name
FGB (FGB Products )
Synonyms
FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGB,HEL-S-78p,Cardiovascular,Blood,Coagulation,FGB
Molecular Weight
55 kDa
Gene ID
2244
UniProt
P02675
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