F11R antibody (AA 30-238)

Catalog No. ABIN3021823

Product Details anti-F11R Antibody

Target: F11R (F11 Receptor (F11R))

Binding Specificity: AA 30-238

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TVHSSEPEVR IPENNPVKLS CAYSGFSSPR VEWKFDQGDT TRLVCYNNKI TASYEDRVTF LPTGITFKSV TREDTGTYTC MVSEEGGNSY GEVKVKLIVL VPPSKPTVNI PSSATIGNRA VLTCSEQDGS PPSEYTWFKD GIVMPTNPKS TRAFSNSSYV LNPTTGELVF DPLSASDTGE YSCEARNGYG TPMTSNAVRM EAVERNVGV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-F11R antibody (ABIN3021823)

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R (F11R Products)

Synonyms: CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Blood,F11R

Molecular Weight: 27 kDa/32 kDa

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization