ARHGDIA antibody (AA 1-204)

Catalog No. ABIN3021744

Product Details anti-ARHGDIA Antibody

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Binding Specificity: AA 1-204

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MAEQEPTAEQ LAQIAAENEE DEHSVNYKPP AQKSIQEIQE LDKDDESLRK YKEALLGRVA VSADPNVPNV VVTGLTLVCS SAPGPLELDL TGDLESFKKQ SFVLKEGVEY RIKISFRVNR EIVSGMKYIQ HTYRKGVKID KTDYMVGSYG PRAEEYEFLT PVEEAPKGML ARGSYSIKSR FTDDDKTDHL SWEWNLTIKK DWKD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human RhoGDI (NP_001172006.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: ARHGDIA (ARHGDIA Products)

Synonyms: GDIA1 antibody, NPHS8 antibody, RHOGDI antibody, RHOGDI-1 antibody, Bles01 antibody, zgc:55554 antibody, zgc:77681 antibody, wu:fa96g11 antibody, ARHGDIA antibody, NV15502 antibody, 5330430M07Rik antibody, Gdi-1 antibody, Rho-GDI antibody, RhoDGI antibody, RhoGDI-1 antibody, arhgdia antibody, MGC84535 antibody, gdia1 antibody, rhogdi antibody, rhogdi-1 antibody, rhogdi1 antibody, Rho GDP dissociation inhibitor alpha antibody, Rho GDP dissociation inhibitor (GDI) alpha antibody, rho GDP-dissociation inhibitor 2 antibody, Rho GDP dissociation inhibitor (GDI) alpha L homeolog antibody, ARHGDIA antibody, Arhgdia antibody, arhgdia antibody, LOC100120432 antibody, arhgdia.L antibody

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.,ARHGDIA,GDIA1,HEL-S-47e,NPHS8,RHOGDI,RHOGDI-1,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ARHGDIA

Molecular Weight: 18 kDa/23 kDa

Gene ID: 396

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway