UGDH antibody (AA 165-494)

Catalog No. ABIN3021733

Product Details anti-UGDH Antibody

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Binding Specificity: AA 165-494

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGDH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EGTAIKDLKN PDRVLIGGDE TPEGQRAVQA LCAVYEHWVP REKILTTNTW SSELSKLAAN AFLAQRISSI NSISALCEAT GADVEEVATA IGMDQRIGNK FLKASVGFGG SCFQKDVLNL VYLCEALNLP EVARYWQQVI DMNDYQRRRF ASRIIDSLFN TVTDKKIAIL GFAFKKDTGD TRESSSIYIS KYLMDEGAHL HIYDPKVPRE QIVVDLSHPG VSEDDQVSRL VTISKDPYEA CDGAHAVVIC TEWDMFKELD YERIHKKMLK PAFIFDGRRV LDGLHNELQT IGFQIETIGK KVSSKRIPYA PSGEIPKFSL QDPPNKKPKV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Alternative Name: UGDH (UGDH Products)

Synonyms: 8310 antibody, BG01214 antibody, CG10072 antibody, Dmel\\CG10072 antibody, Sgl antibody, UDP-GlcDH antibody, UDPGDH antibody, XIII antibody, kiwi antibody, l(3)05007 antibody, l(3)08310 antibody, l(3)10503 antibody, l(3)65CEd antibody, l(3)SG9 antibody, ska antibody, sl antibody, ik:tdsubc_2a8 antibody, tdsubc_2a8 antibody, xx:tdsubc_2a8 antibody, gdh antibody, ugd antibody, ugdh antibody, ugdhb antibody, xugdh antibody, udpgdh antibody, udpg antibody, ugdha antibody, BA5434 antibody, SCBAC19G2.07 antibody, AGR_L_1413 antibody, udg antibody, GDH antibody, UGD antibody, Udpgdh antibody, sugarless antibody, UDP-glucose 6-dehydrogenase antibody, UDP-glucose 6-dehydrogenase L homeolog antibody, UDP-glucose 6-dehydrogenase S homeolog antibody, UDP-glucose dehydrogenase WcvB antibody, UDP-glucose dehydrogenase antibody, sgl antibody, ugdh antibody, ugdh.L antibody, UGDH antibody, ugdh.S antibody, hasB antibody, ugdH antibody, ugd antibody, SCO3052 antibody, wcvB antibody, CNL06460 antibody, Ugdh antibody

Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.,UGDH,GDH,UDP-GlcDH,UDPGDH,UGD,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,UGDH

Molecular Weight: 44 kDa/47 kDa/55 kDa

Gene ID: 7358

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process