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Tropomyosin antibody (AA 1-245)

TPM1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021578
  • Target See all Tropomyosin (TPM1) Antibodies
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    Binding Specificity
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-245
    Reactivity
    • 42
    • 33
    • 31
    • 11
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 12
    Rabbit
    Clonality
    • 34
    • 21
    Polyclonal
    Conjugate
    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Tropomyosin antibody is un-conjugated
    Application
    • 29
    • 20
    • 10
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE DADRKYEEVA RKLVIIESDL ERAEERAELS EGKCAELEEE LKTVTNNLKS LEAQAEKYSQ KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EDQLYQQLEQ NRRLTNELKL ALNED
    Cross-Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio)
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human Tropomyosin 1 (NP_001018008.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wu, Lou, Ge, Xiong: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).

  • Target
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    Alternative Name
    TPM1 (TPM1 Products)
    Synonyms
    alpha-fTM antibody, Tm7 antibody, tpm1 antibody, MGC84844 antibody, AA986836 antibody, AI854628 antibody, TM2 antibody, Tm3 antibody, Tmpa antibody, Tpm-1 antibody, alpha-TM antibody, Alpha-tm antibody, Tma2 antibody, Tmsa antibody, TPM1 antibody, fb37a09 antibody, tm antibody, wu:fb37a09 antibody, CH1 antibody, alpha-tm antibody, alpha-tropomyosin antibody, C15orf13 antibody, CMD1Y antibody, CMH3 antibody, HTM-alpha antibody, TMSA antibody, TPMA antibody, Tm1 antibody, zgc:171719 antibody, zgc:55951 antibody, zgc:77009 antibody, tropomyosin 1 (alpha) antibody, tropomyosin antibody, tropomyosin 1 antibody, tropomyosin 1, alpha antibody, alpha-tropomyosin antibody, tropomyosin 1 L homeolog antibody, TPM1 antibody, tm7 antibody, Tpm1 antibody, tpma antibody, tpm1.L antibody, Smp_044010.2 antibody, LOC732984 antibody, tpm1 antibody
    Background
    This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.,TPM1,C15orf13,CMD1Y,CMH3,HEL-S-265,HTM-alpha,LVNC9,TMSA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Hypertrophy,TPM1
    Molecular Weight
    26 kDa/28 kDa/32 kDa
    Gene ID
    7168
    UniProt
    P09493
    Pathways
    Regulation of Actin Filament Polymerization
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