Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Cardiac troponin T (Cardiac troponin T (TNNT2)) (NP_001001431.1).
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.,TNNT2,CMD1D,CMH2,CMPD2,LVNC6,RCM3,TnTC,cTnT,troponin T2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Cardiovascular Markers,Cardiomyocytes,Heart,Contractility,TNNT2