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NUAK2 antibody (AA 523-672)
NUAK2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUAK2 Antibody
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Target
See all NUAK2 Antibodies
NUAK2
(NUAK Family, SNF1-Like Kinase, 2 (NUAK2))
Binding Specificity
All epitopes for NUAK2 antibodies
AA 523-672
Reactivity
All reactivities for NUAK2 antibodies
Human
Host
All hosts for NUAK2 antibodies
Rabbit
Clonality
All clonalities for NUAK2 antibodies
Polyclonal
Conjugate
All conjugates for NUAK2 antibodies
This NUAK2 antibody is un-conjugated
Application
All applications for NUAK2 antibodies
Western Blotting (WB)
Sequence
VSGDPKEQKP PQASGLLLHR KGILKLNGKF SQTALELAAP TTFGSLDELA PPRPLARASR PSGAVSEDSI LSSESFDQLD LPERLPEPPL RGCVSVDNLT GLEEPPSEGP GSCLRRWRQD PLGDSCFSLT DCQEVTATYR QALRVCSKLT
Cross-Reactivity
Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 523-672 of human NUAK2 (NP_112214.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NUAK2
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Target
NUAK2
(NUAK Family, SNF1-Like Kinase, 2 (NUAK2))
Alternative Name
NUAK2 (NUAK2 Products )
Synonyms
SNARK antibody, 1200013B22Rik antibody, Omphk2 antibody, Snark antibody, mKIAA0537 antibody, 1200013b22rik antibody, UV126 antibody, NUAK family kinase 2 antibody, NUAK family, SNF1-like kinase, 2 antibody, NUAK2 antibody, Nuak2 antibody
Background
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.,NUAK2,SNARK,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,NUAK2
Molecular Weight
69 kDa
Gene ID
81788
UniProt
Q9H093
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