PRMT1 antibody (AA 20-353)

Catalog No. ABIN3021312

Product Details anti-PRMT1 Antibody

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Binding Specificity: AA 20-353

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: SSEKPNAEDM TSKDYYFDSY AHFGIHEEML KDEVRTLTYR NSMFHNRHLF KDKVVLDVGS GTGILCMFAA KAGARKVIGI ECSSISDYAV KIVKANKLDH VVTIIKGKVE EVELPVEKVD IIISEWMGYC LFYESMLNTV LYARDKWLAP DGLIFPDRAT LYVTAIEDRQ YKDYKIHWWE NVYGFDMSCI KDVAIKEPLV DVVDPKQLVT NACLIKEVDI YTVKVEDLTF TSPFCLQVKR NDYVHALVAY FNIEFTRCHK RTGFSTSPES PYTHWKQTVF YMEDYLTVKT GEEIFGTIGM RPNAKNNRDL DFTIDLDFKG QLCELSCSTD YRMR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-353 of human PRMT1 (NP_938074.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Alternative Name: PRMT1 (PRMT1 Products)

Background: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.,PRMT1,ANM1,HCP1,HRMT1L2,IR1B4,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,PRMT1

Molecular Weight: 39 kDa/40 kDa/41 kDa

Gene ID: 3276

UniProt: Q99873