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ARNT antibody (AA 400-500)

ARNT Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021191
  • Target See all ARNT Antibodies
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    Binding Specificity
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-500
    Reactivity
    • 56
    • 22
    • 21
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 44
    • 12
    • 3
    Rabbit
    Clonality
    • 38
    • 21
    Polyclonal
    Conjugate
    • 45
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ARNT antibody is un-conjugated
    Application
    • 41
    • 14
    • 13
    • 11
    • 11
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    CHPEDQQLLR DSFQQVVKLK GQVLSVMFRF RSKNQEWLWM RTSSFTFQNP YSDEIEYIIC TNTNVKNSSQ EPRPTLSNTI QRPQLGPTAN LPLEMGSGQL A
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HIF1beta/ARNT (NP_001659.1).
    Isotype
    IgG
    Top Product
    Discover our top product ARNT Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    Alternative Name
    ARNT (ARNT Products)
    Synonyms
    HIF-1-beta antibody, HIF-1beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1BETA antibody, TANGO antibody, bHLHe2 antibody, D3Ertd557e antibody, Drnt antibody, ESTM42 antibody, Hif1b antibody, W08714 antibody, mKIAA4051 antibody, Arnt1 antibody, ARNT antibody, zgc:136664 antibody, arnt1 antibody, hif1b antibody, tango antibody, xArnt antibody, hif1beta antibody, hif-1beta antibody, arnt.2 antibody, MGC68805 antibody, aryl hydrocarbon receptor nuclear translocator antibody, aryl hydrocarbon receptor nuclear translocator S homeolog antibody, ARNT antibody, Arnt antibody, arnt antibody, arnt.S antibody
    Background
    This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.,ARNT,HIF-1-beta,HIF-1beta,HIF1-beta,HIF1B,HIF1BETA,TANGO,bHLHe2,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Invasion and Metastasis,Signal Transduction,mTOR Signaling Pathway,Endocrine & Metabolism,Nucleotide metabolism,Cardiovascular,Angiogenesis,Hypoxia,HIF,ARNT
    Molecular Weight
    84 kDa/85 kDa/86 kDa
    Gene ID
    405
    UniProt
    P27540
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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