MMP7 antibody (AA 18-267)

Catalog No. ABIN3021103

Product Details anti-MMP7 Antibody

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Binding Specificity: AA 18-267

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: LPLPQEAGGM SELQWEQAQD YLKRFYLYDS ETKNANSLEA KLKEMQKFFG LPITGMLNSR VIEIMQKPRC GVPDVAEYSL FPNSPKWTSK VVTYRIVSYT RDLPHITVDR LVSKALNMWG KEIPLHFRKV VWGTADIMIG FARGAHGDSY PFDGPGNTLA HAFAPGTGLG GDAHFDEDER WTDGSSLGIN FLYAATHELG HSLGMGHSSD PNAVMYPTYG NGDPQNFKLS QDDIKGIQKL YGKRSNSRKK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human MMP7 (NP_002414.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MMP7

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Alternative Name: MMP7 (MMP7 Products)

Synonyms: MAT antibody, MPMM antibody, MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, matrilysin antibody, LOC727698 antibody, MMP7 antibody, Matrilysin antibody, matrix metallopeptidase 7 antibody, MMP7 antibody, Mmp7 antibody

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.,MMP7,MMP-7,MPSL1,PUMP-1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP7

Molecular Weight: 29 kDa

Gene ID: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response