ATG7 antibody (AA 500-676)

Catalog No. ABIN3021091

Product Details anti-ATG7 Antibody

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Binding Specificity: AA 500-676

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: LGFDTFVVMR HGLKKPKQQG AGDLCPNHPV ASADLLGSSL FANIPGYKLG CYFCNDVVAP GDSTRDRTLD QQCTVSRPGL AVIAGALAVE LMVSVLQHPE GGYAIASSSD DRMNEPPTSL GLVPHQVLDQ YEREGFNFLA KVFNSSHSFL EDLTGLTLLH QETQAAEIWD MSDDETI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-676 of human ATG7 (NP_001129503.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7 (ATG7 Products)

Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.,ATG7,APG7-LIKE,APG7L,GSA7,Apg7/Atg7,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Immunology & Inflammation,Cardiovascular,Heart,ATGs,ATG7

Molecular Weight: 68 kDa/75 kDa/77 kDa

Gene ID: 10533

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy