Neuregulin 1 antibody (AA 20-241)
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- Target See all Neuregulin 1 (NRG1) Antibodies
- Neuregulin 1 (NRG1)
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Binding Specificity
- AA 20-241
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Neuregulin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- SGKKPESAAG SQSPALPPRL KEMKSQESAA GSKLVLRCET SSEYSSLRFK WFKNGNELNR KNKPQNIKIQ KKPGKSELRI NKASLADSGE YMCKVISKLG NDSASANITI VESNEIITGM PASTEGAYVS SESPIRISVS TEGANTSSST STSTTGTSHL VKCAEKEKTF CVNGGECFMV KDLSNPSRYL CKCPNEFTGD RCQNYVMASF YSTSTPFLSL PE
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-241 of human NRG1 (NP_039252.2).
- Isotype
- IgG
- Top Product
- Discover our top product NRG1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Neuregulin 1 (NRG1)
- Alternative Name
- NRG1 (NRG1 Products)
- Synonyms
- 6030402G23Rik antibody, ARIA antibody, D230005F13Rik antibody, GGF antibody, GGFII antibody, HRG antibody, HRGalpha antibody, Hgl antibody, NDF antibody, SMDF antibody, GGF2 antibody, HGL antibody, HRG1 antibody, HRGA antibody, MST131 antibody, NRG-1 antibody, heregulin antibody, nrg1-A antibody, pro-neuregulin-1 antibody, NRG1 antibody, wu:fm70e01 antibody, DKFZp459A1838 antibody, neuregulin 1 antibody, histidine rich glycoprotein antibody, neuregulin 1 L homeolog antibody, Nrg1 antibody, NRG1 antibody, HRG antibody, nrg1.L antibody, nrg1 antibody
- Background
- The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).,NRG1,ARIA,GGF,GGF2,HGL,HRG,HRG1,HRGA,MST131,MSTP131,NDF,NRG1-IT2,SMDF,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Cell Type Marker,Oligodendrocyte marker,NRG1
- Molecular Weight
- 26 kDa/31 kDa/45- 50 kDa/65-71 kDa
- Gene ID
- 3084
- UniProt
- Q02297
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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