DOK4 antibody (AA 240-326)

Catalog No. ABIN3020722

Product Details anti-DOK4 Antibody

Target: DOK4 (Docking Protein 4 (DOK4))

Binding Specificity: AA 240-326

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: EMEKNVRLLN KGTEHYSYPC TPTTMLPRSA YWHHITGSQN IAEASSYAGE GYGAAQASSE TDLLNRFILL KPKPSQGDSS EAKTPSQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-326 of human DOK4 (NP_060580.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DOK4

Target: DOK4 (Docking Protein 4 (DOK4))

Alternative Name: DOK4 (DOK4 Products)

Synonyms: DOK4 antibody, docking protein 4 antibody, DOK4 antibody, Dok4 antibody

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.,DOK4,IRS-5,IRS5,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,DOK4

Molecular Weight: 37 kDa

Gene ID: 55715

UniProt: Q8TEW6