TUBB antibody (AA 40-260)

Catalog No. ABIN3020553

Product Details anti-TUBB Antibody

Target: TUBB (Tubulin, beta (TUBB))

Binding Specificity: AA 40-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: SDLQLERISV YYNEASSHKY VPRAILVDLE PGTMDSVRSG AFGHLFRPDN FIFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKECENCDC LQGFQLTHSL GGGTGSGMGT LLISKVREEY PDRIMNTFSV VPSPKVSDTV VEPYNATLSI HQLVENTDET YCIDNEALYD ICFRTLKLAT PTYGDLNHLV SATMSGVTTS LRFPGQLNAD LRKLAVNMVP F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Loading control Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human beta-Tubulin (NP_006077.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:5000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TUBB antibody (ABIN3020553)

Li, Wu, Yuan, Sun, Lin, Huang, Bin, Liao, Liao: "Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis." in: Cancer letters, Vol. 395, pp. 31-44, (2017) (PubMed).

Jiang, Liu, Zhou, Wang, Wang, Yue, Wang, Wang, Song: "Transcriptional activation and translocation of ancient NOS during immune response." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 10, pp. 3527-3540, (2017) (PubMed).

Liu, Shang, Xiao, Zhong, Cheng, Zhou: "Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice." in: The Journal of biological chemistry, Vol. 292, Issue 39, pp. 16003-16013, (2017) (PubMed).

Wang, Wang, Xu, Jia, Liu, Wang, Song: "Soluble adenylyl cyclase mediates mitochondrial pathway of apoptosis and ATP metabolism in oyster Crassostrea gigas exposed to elevated CO2." in: Fish & shellfish immunology, Vol. 66, pp. 140-147, (2017) (PubMed).

Tian, Tao, Chen, Li, Li, Shang, Tang, Chen, Tang: "Electroacupuncture Treatment Alleviates Central Poststroke Pain by Inhibiting Brain Neuronal Apoptosis and Aberrant Astrocyte Activation." in: Neural plasticity, Vol. 2016, pp. 1437148, (2017) (PubMed).

Lai, Gu, Zhao, Li, Ma, Luo, Liu: "Toxic effect of acrylamide on the development of hippocampal neurons of weaning rats." in: Neural regeneration research, Vol. 12, Issue 10, pp. 1648-1654, (2017) (PubMed).

Sun, Luo, Deng, Zhang, Chen: "The study on mechanism of the modified Chinese herbal compound, jianpijiedu, on a mouse model of hepatic carcinoma cachexia." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3113-21, (2017) (PubMed).

Sun, Wang, Jiang, Liu, Zhao, Chen, Song, Song: "CpG ODNs induced autophagy via reactive oxygen species (ROS) in Chinese mitten crab, Eriocheir sinensis." in: Developmental and comparative immunology, Vol. 52, Issue 1, pp. 1-9, (2016) (PubMed).

Target Details for TUBB

Target: TUBB (Tubulin, beta (TUBB))

Alternative Name: TUBB (TUBB Products)

Background: This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.,CDCBM6,CSCSC1,M40,OK/SW-cl.56,TUBB1,TUBB5,Beta Tubulin,TUBB,β-Tubulin,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microtubules,TUBB

Molecular Weight: 50 kDa

Gene ID: 203068

UniProt: P07437

Pathways: Microtubule Dynamics, M Phase