TUBB antibody (AA 40-260)

Catalog No. ABIN3020553

Product Details anti-TUBB Antibody

Target: TUBB (Tubulin, beta (TUBB))

Binding Specificity: AA 40-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: SDLQLERISV YYNEASSHKY VPRAILVDLE PGTMDSVRSG AFGHLFRPDN FIFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKECENCDC LQGFQLTHSL GGGTGSGMGT LLISKVREEY PDRIMNTFSV VPSPKVSDTV VEPYNATLSI HQLVENTDET YCIDNEALYD ICFRTLKLAT PTYGDLNHLV SATMSGVTTS LRFPGQLNAD LRKLAVNMVP F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Loading control Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human beta-Tubulin (NP_006077.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:5000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TUBB antibody (ABIN3020553)

Li, Wu, Yuan, Sun, Lin, Huang, Bin, Liao, Liao: "Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis." in: Cancer letters, Vol. 395, pp. 31-44, (2017) (PubMed).

Jiang, Liu, Zhou, Wang, Wang, Yue, Wang, Wang, Song: "Transcriptional activation and translocation of ancient NOS during immune response." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 10, pp. 3527-3540, (2017) (PubMed).

Liu, Shang, Xiao, Zhong, Cheng, Zhou: "Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice." in: The Journal of biological chemistry, Vol. 292, Issue 39, pp. 16003-16013, (2017) (PubMed).

Wang, Wang, Xu, Jia, Liu, Wang, Song: "Soluble adenylyl cyclase mediates mitochondrial pathway of apoptosis and ATP metabolism in oyster Crassostrea gigas exposed to elevated CO2." in: Fish & shellfish immunology, Vol. 66, pp. 140-147, (2017) (PubMed).

Tian, Tao, Chen, Li, Li, Shang, Tang, Chen, Tang: "Electroacupuncture Treatment Alleviates Central Poststroke Pain by Inhibiting Brain Neuronal Apoptosis and Aberrant Astrocyte Activation." in: Neural plasticity, Vol. 2016, pp. 1437148, (2017) (PubMed).

Lai, Gu, Zhao, Li, Ma, Luo, Liu: "Toxic effect of acrylamide on the development of hippocampal neurons of weaning rats." in: Neural regeneration research, Vol. 12, Issue 10, pp. 1648-1654, (2017) (PubMed).

Sun, Luo, Deng, Zhang, Chen: "The study on mechanism of the modified Chinese herbal compound, jianpijiedu, on a mouse model of hepatic carcinoma cachexia." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3113-21, (2017) (PubMed).

Sun, Wang, Jiang, Liu, Zhao, Chen, Song, Song: "CpG ODNs induced autophagy via reactive oxygen species (ROS) in Chinese mitten crab, Eriocheir sinensis." in: Developmental and comparative immunology, Vol. 52, Issue 1, pp. 1-9, (2016) (PubMed).

Target Details for TUBB

Target: TUBB (Tubulin, beta (TUBB))

Alternative Name: TUBB (TUBB Products)

Synonyms: M40 antibody, OK/SW-cl.56 antibody, TUBB1 antibody, TUBB5 antibody, XLOT antibody, m40 antibody, ok/sw-cl.56 antibody, tubb1 antibody, tubb5 antibody, TUBB2A antibody, TUBB2B antibody, TUBB antibody, 1t antibody, B1t antibody, BETA 56D antibody, CG9277 antibody, DTB2 antibody, Dmbeta1 antibody, Dmel\\CG9277 antibody, T antibody, Tub antibody, Tubulin antibody, beta antibody, beta-Tub antibody, beta-Tub56D antibody, beta-tub antibody, beta-tubulin56D antibody, beta1 antibody, beta1-Tubulin antibody, beta1-tub antibody, beta1Tub antibody, beta1t antibody, beta1tub antibody, beta56D antibody, betaTub antibody, betaTub1 antibody, beta[[1]] tubulin antibody, beta[[1]]-tubulin antibody, betatub(56D) antibody, 143391_i_at antibody, 3t antibody, B3t antibody, BETA 60D antibody, CG3401 antibody, D.m.BETA-60D antibody, DTB3 antibody, Dmbeta3 antibody, Dmel\\CG3401 antibody, Tub60D antibody, beta-Tub60D antibody, beta-Tub6D antibody, beta3 antibody, beta3 TU antibody, beta3-Tub antibody, beta3-tubulin antibody, beta3TUB antibody, beta3Tub antibody, beta3t antibody, beta60C antibody, betaTub3 antibody, betaTub60C antibody, beta[[3]] tubulin antibody, beta[[3]]-Tub antibody, beta[[3]]-tubulin antibody, betatub60D antibody, p50 antibody, p50/tubulin antibody, p53 antibody, p53/tubulin antibody, 2t antibody, B2t antibody, BETA 85D antibody, BETA2 antibody, CG9359 antibody, D.m.BETA-85D antibody, DTB4 antibody, Dmbeta2 antibody, Dmel\\CG9359 antibody, beta(2)Tu antibody, beta(2)Tub antibody, beta-Tub85D antibody, beta-tub85D antibody, beta2 antibody, beta2-tub antibody, beta2t antibody, beta2tub antibody, beta85D antibody, betaTub2 antibody, beta[[2]]-tubulin antibody, ms(3)KK[D] antibody, 4t antibody, B4t antibody, BETA 98B antibody, CG4869 antibody, DTB1 antibody, Dmbeta4 antibody, Dmel\\CG4869 antibody, beta-Tub97EF antibody, beta4 antibody, beta4t antibody, beta97F antibody, betaTub4 antibody, betaTub98BC antibody, betaTub98C antibody, Tub1 antibody, bmtub1 antibody, Tub3 antibody, bmtub3 antibody, Tub2 antibody, bmtub2 antibody, Tub4 antibody, bmtub4 antibody, LOC100101153 antibody, tubulin beta class I antibody, putative cobalt-zinc-cadmium outer membrane resistance protein antibody, Tubulin beta chain antibody, tubulin beta-2A chain antibody, beta-Tubulin at 56D antibody, beta-Tubulin at 60D antibody, beta-Tubulin at 85D antibody, beta-Tubulin at 97EF antibody, beta-tubulin antibody, tubulin beta 6 class V antibody, beta tubulin antibody, tubulin beta class I L homeolog antibody, tubulin, beta 5 class I antibody, TUBB antibody, czcC antibody, tbb-6 antibody, tubb antibody, LOC462399 antibody, betaTub56D antibody, betaTub60D antibody, betaTub85D antibody, betaTub97EF antibody, Tub1 antibody, Tub3 antibody, Tub2 antibody, Tub4 antibody, TVAG_525430 antibody, TVAG_062880 antibody, TVAG_456920 antibody, LOC100101153 antibody, TUBB6 antibody, Tb927.1.2330 antibody, Tb927.1.2350 antibody, Tb927.1.2370 antibody, Tb927.1.2390 antibody, tubb.L antibody, Tubb antibody, LOC693049 antibody, LOC443015 antibody, Tubb5 antibody

Background: This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.,CDCBM6,CSCSC1,M40,OK/SW-cl.56,TUBB1,TUBB5,Beta Tubulin,TUBB,β-Tubulin,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microtubules,TUBB

Molecular Weight: 50 kDa

Gene ID: 203068

UniProt: P07437

Pathways: Microtubule Dynamics, M Phase