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Acetyl-CoA Carboxylase alpha antibody (pSer79)
ACACA
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Acetyl-CoA Carboxylase alpha Antibody
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Target
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Acetyl-CoA Carboxylase alpha (ACACA)
Binding Specificity
All epitopes for Acetyl-CoA Carboxylase alpha antibodies
pSer79
Reactivity
All reactivities for Acetyl-CoA Carboxylase alpha antibodies
Human
Host
All hosts for Acetyl-CoA Carboxylase alpha antibodies
Rabbit
Clonality
All clonalities for Acetyl-CoA Carboxylase alpha antibodies
Polyclonal
Conjugate
All conjugates for Acetyl-CoA Carboxylase alpha antibodies
This Acetyl-CoA Carboxylase alpha antibody is un-conjugated
Application
All applications for Acetyl-CoA Carboxylase alpha antibodies
Western Blotting (WB)
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Phosphorylated Antibodies
Purification
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding S79 of human ACC1
Isotype
IgG
Top Product
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-Acetyl-CoA Carboxylase alpha antibody (ABIN3020067)
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Li, Zhao, Chen, Fu, Shi, Liu, Liu, Xiong, Liu, Yang, Xiao : "Depsidone and xanthones from Garcinia xanthochymus with hypoglycemic activity and the mechanism of promoting glucose uptake in L6 myotubes. " in: Bioorganic & medicinal chemistry , Vol. 25 , Issue 24 , pp. 6605-6613 , (2017 ) (PubMed ).
Target Details for Acetyl-CoA Carboxylase alpha
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Target
Acetyl-CoA Carboxylase alpha (ACACA)
Alternative Name
ACC1 (ACACA Products )
Synonyms
ACAC antibody, ACACAD antibody, ACC antibody, ACC1 antibody, ACCA antibody, A530025K05Rik antibody, Acac antibody, Acc1 antibody, Gm738 antibody, AT-ACC1 antibody, EMB22 antibody, EMBRYO DEFECTIVE 22 antibody, GK antibody, GURKE antibody, PAS3 antibody, PASTICCINO 3 antibody, acetyl-CoA carboxylase 1 antibody, acc antibody, fj43d01 antibody, im:7138837 antibody, si:ch211-199d18.1 antibody, wu:fj43d01 antibody, acetyl-CoA carboxylase alpha antibody, acetyl-Coenzyme A carboxylase alpha antibody, acetyl-CoA carboxylase 1 antibody, ACACA antibody, Acaca antibody, ACC1 antibody, acaca antibody
Background
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.,ACACA,ACAC,ACACAD,ACC,ACC1,ACCA,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Warburg Effect,Protein phosphorylation,ACC1
Molecular Weight
257 kDa/259 kDa/265 kDa/269 kDa
Gene ID
31
UniProt
Q13085
Pathways
AMPK Signaling , Ribonucleoside Biosynthetic Process , Warburg Effect
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