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Cofilin antibody (pSer3)
CFL1
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Cofilin Antibody
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Target
See all Cofilin (CFL1) Antibodies
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Binding Specificity
All epitopes for Cofilin antibodies
pSer3
Reactivity
All reactivities for Cofilin antibodies
Human
Host
All hosts for Cofilin antibodies
Rabbit
Clonality
All clonalities for Cofilin antibodies
Polyclonal
Conjugate
All conjugates for Cofilin antibodies
This Cofilin antibody is un-conjugated
Application
All applications for Cofilin antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Phosphorylated Antibodies
Purification
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
Isotype
IgG
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Discover our top product CFL1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-Cofilin antibody (ABIN3019728)
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Hu, Guo, Feng, Zhang, Zhou, Ma, Shen, Tong, Yan, Zhu, Bian, Lai, Deng, Ding : "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis. " in: Oncotarget , Vol. 6 , Issue 26 , pp. 22410-23 , (2016 ) (PubMed ).
Target Details for Cofilin
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Target
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Alternative Name
CFL1 (CFL1 Products )
Synonyms
cfl1 antibody, xac1 antibody, xac2 antibody, cfl antibody, cb86 antibody, sb:cb86 antibody, zgc:56501 antibody, wu:fb18a04 antibody, wu:fk77b03 antibody, 12/8 antibody, ADF antibody, ADF/cofilin antibody, Adf antibody, CG4254 antibody, Cadf antibody, D-cof antibody, D61 antibody, Dmel\\CG4254 antibody, T8 antibody, Tsr antibody, cofilin antibody, cofilin/ADF antibody, cofilin/actin depolymerizing factor homolog antibody, l(2)03101 antibody, l(2)k03101 antibody, l(2)k05633 antibody, l(2)k13409 antibody, ntf antibody, CFL antibody, AA959946 antibody, Cof antibody, CFL1 antibody, cofilin 1 (non-muscle) L homeolog antibody, cofilin 1 (non-muscle) antibody, cofilin 1 (non-muscle), like antibody, cofilin 1 antibody, twinstar antibody, cofilin antibody, cofilin 1, non-muscle antibody, Contrafreeloading antibody, cfl1.L antibody, cfl1 antibody, cfl1l antibody, CFL1 antibody, tsr antibody, COF1 antibody, TSTA_042790 antibody, Cfl1 antibody, CFL antibody
Background
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],CFL1,CFL,HEL-S-15,cofilin,cofilin-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Contractility,Neuron marker,Axon marker,Protein phosphorylation,CFL1
Molecular Weight
18 kDa
Gene ID
1072
UniProt
P23528
Pathways
Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus , CXCR4-mediated Signaling Events
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