TBK1 antibody (AA 440-729)

Catalog No. ABIN3016268

Product Details anti-TBK1 Antibody

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Binding Specificity: AA 440-729

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RKGIRWLIEL IKDDYNETVH KKTEVVITLD FCIRNIEKTV KVYEKLMKIN LEAAELGEIS DIHTKLLRLS SSQGTIETSL QDIDSRLSPG GSLADAWAHQ EGTHPKDRNV EKLQVLLNCM TEIYYQFKKD KAERRLAYNE EQIHKFDKQK LYYHATKAMT HFTDECVKKY EAFLNKSEEW IRKMLHLRKQ LLSLTNQCFD IEEEVSKYQE YTNELQETLP QKMFTASSGI KHTMTPIYPS SNTLVEMTLG MKKLKEEMEG VVKELAENNH ILERFGSLTM DGGLRNVDCL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 440-729 of human TBK1/NAK (NP_037386.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1 (TBK1 Products)

Synonyms: nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody

Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.,TBK1,FTDALS4,NAK,T2K,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Kinase of Akt,TBK1

Molecular Weight: 83 kDa

Gene ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome