MAP2 antibody (AA 260-559)

Catalog No. ABIN3016265

Product Details anti-MAP2 Antibody

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Binding Specificity: AA 260-559

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: DENSFSLNSS ISSSARRTTR SEPIRRAGKS GTSTPTTPGS TAITPGTPPS YSSRTPGTPG TPSYPRTPHT PGTPKSAILV PSEKKVAIIR TPPKSPATPK QLRLINQPLP DLKNVKSKIG STDNIKYQPK GGQVRILNKK IDFSKVQSRC GSKDNIKHSA GGGNVQIVTK KIDLSHVTSK CGSLKNIRHR PGGGRVKIES VKLDFKEKAQ AKVGSLDNAH HVPGGGNVKI DSQKLNFREH AKARVDHGAE IITQSPGRSS VASPRRLSNV SSSGSINLLE SPQLATLAED VTAALAKQGL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-559 of human MAP2 (NP_001034627.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MAP2 antibody (ABIN3016265)

Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

Wang, Zhu, Li, Yang, Xiao, Kang, Li, Zhao, Zeng, Li, Zhang, He, Ying et al.: "Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine ..." in: Journal of agricultural and food chemistry, Vol. 64, Issue 7, pp. 1528-39, (2016) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: Map2 (MAP2 Products)

Synonyms: MAP2A antibody, MAP2B antibody, MAP2C antibody, MAP2R antibody, Mtap2 antibody, MAP-2 antibody, Mtap-2 antibody, xmap2 antibody, MGC53131 antibody, a730034c02 antibody, zgc:103474 antibody, zgc:113974 antibody, microtubule associated protein 2 antibody, microtubule-associated protein 2 antibody, microtubule associated protein 2 S homeolog antibody, MAP2 antibody, Map2 antibody, map2.S antibody, map2 antibody

Background: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.,MAP2,MAP2A,MAP2B,MAP2C,Map2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microtubules,Neuroscience,Cell Type Marker,Stem Cells,Neuron marker,Map2

Molecular Weight: 49 kDa/58 kDa/199 kDa

Gene ID: 4133

UniProt: P11137