PRG2 antibody (AA 17-222)

Catalog No. ABIN3016204

Product Details anti-PRG2 Antibody

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Binding Specificity: AA 17-222

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: LHLRSETSTF ETPLGAKTLP EDEETPEQEM EETPCRELEE EEEWGSGSED ASKKDGAVES ISVPDMVDKN LTCPEEEDTV KVVGIPGCQT CRYLLVRSLQ TFSQAWFTCR RCYRGNLVSI HNFNINYRIQ CSVSALNQGQ VWIGGRITGS GRCRRFQWVD GSRWNFAYWA AHQPWSRGGH CVALCTRGGH WRRAHCLRRL PFICSY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2 (NP_002719.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRG2

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Alternative Name: PRG2 (PRG2 Products)

Synonyms: MBP antibody, mMBP antibody, mMBP-1 antibody, BMPG antibody, MBP1 antibody, proteoglycan 2, bone marrow antibody, proteoglycan 2 antibody, proteoglycan 2, pro eosinophil major basic protein antibody, Prg2 antibody, PRG2 antibody

Background: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PRG2,BMPG,MBP,MBP1,proMBP,PRG2

Molecular Weight: 23 kDa/25 kDa

Gene ID: 5553

UniProt: P13727