KPNA4 antibody (AA 1-240)

Catalog No. ABIN3015855

Product Details anti-KPNA4 Antibody

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Binding Specificity: AA 1-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MADNEKLDNQ RLKNFKNKGR DLETMRRQRN EVVVELRKNK RDEHLLKRRN VPHEDICEDS DIDGDYRVQN TSLEAIVQNA SSDNQGIQLS AVQAARKLLS SDRNPPIDDL IKSGILPILV HCLERDDNPS LQFEAAWALT NIASGTSEQT QAVVQSNAVP LFLRLLHSPH QNVCEQAVWA LGNIIGDGPQ CRDYVISLGV VKPLLSFISP SIPITFLRNV TWVMVNLCRH KDPPPPMETI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KPNA4 (NP_002259.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-KPNA4 antibody (ABIN3015855)

Li, Lu, Huang, Lv: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).

Target Details for KPNA4

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Alternative Name: KPNA4 (KPNA4 Products)

Synonyms: IPOA3 antibody, QIP1 antibody, SRP3 antibody, 6 antibody, ATIMPALPHA3 antibody, IMPA-3 antibody, IMPORTIN ALPHA 3 antibody, IMPORTIN ALPHA ISOFORM 3 antibody, MODIFIER OF SNC1 antibody, T10M13.16 antibody, T10M13_16 antibody, LOC100224013 antibody, 1110058D08Rik antibody, importin antibody, ipoa3 antibody, qip1 antibody, srp3 antibody, impa3 antibody, wu:fa56d07 antibody, wu:fa66g10 antibody, wu:fe14c04 antibody, wu:fi04h11 antibody, wu:fi19b05 antibody, karyopherin subunit alpha 4 antibody, ARM repeat superfamily protein antibody, importin alpha 3 antibody, karyopherin (importin) alpha 4 antibody, karyopherin alpha 4 (importin alpha 3) S homeolog antibody, karyopherin alpha 4 (importin alpha 3) antibody, KPNA4 antibody, MOS6 antibody, LOC100533341 antibody, Kpna4 antibody, kpna4.S antibody, kpna4 antibody

Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.,KPNA4,IPOA3,QIP1,SRP3,Signal Transduction,KPNA4

Molecular Weight: 57 kDa

Gene ID: 3840

UniProt: O00629

Pathways: Protein targeting to Nucleus