TNNC1 antibody (AA 1-160)

Catalog No. ABIN3015719

Product Details anti-TNNC1 Antibody

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Binding Specificity: AA 1-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLDELKIM LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1 (NP_003271.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNNC1

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Alternative Name: TNNC1 (TNNC1 Products)

Background: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase, TnT, which contains the binding site for tropomyosin, and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.,TNNC1,CMD1Z,CMH13,TN-C,TNC,TNNC,troponin C1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Heart,Contractility,TNNC1

Molecular Weight: 18 kDa

Gene ID: 7134

UniProt: P63316