CD39 antibody (PE)

Catalog No. ABIN2967171

Product Details anti-CD39 Antibody (PE)

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD39 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody TU66, also known as Tü66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.

Cross-Reactivity (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Clone: TU66

Isotype: IgG2b kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Comment:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CD39

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Alternative Name: CD39 (ENTPD1 Products)

Synonyms: ATPDase antibody, CD39 antibody, NTPDase-1 antibody, MGC80631 antibody, zgc:100819 antibody, entpd1 antibody, MGC79567 antibody, 2610206B08Rik antibody, AA408691 antibody, Cd39 antibody, ectonucleoside triphosphate diphosphohydrolase 1 antibody, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog antibody, ENTPD1 antibody, Entpd1 antibody, entpd1.L antibody, entpd1 antibody

Background: Ectonucleoside triphosphate diphosphohydrolase 1,CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.,ETDH1, LCAA, Ecto-ATPase 1, Ecto-apyrase, ENTPD1

Gene ID: 953

UniProt: P49961