CXCR4 antibody
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- Target See all CXCR4 Antibodies
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Reactivity
- Human, Non-Human Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CXCR4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Specificity
- The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
- Cross-Reactivity (Details)
- Human, Non-Human Primates
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- CP-MAC-infected Sup-T1 cells
- Clone
- 12G5
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CXCR4 Primary Antibody
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anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 201-294) antibody
CXCR4 Reactivity: Human, Mouse, Rat, Rabbit WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G9 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 262-352) antibodyCXCR4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term) antibodyCXCR4 Reactivity: Human, Mouse, Rabbit, Pig, Horse WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 14-40) antibodyCXCR4 Reactivity: Human, Mouse WB, ELISA, IHC, IHC (p) Host: Goat Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-356) antibodyCXCR4 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibodyCXCR4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) antibody (PE)CXCR4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 12G5 PE
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1F8 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 2-15), (Extracellular), (N-Term) antibodyCXCR4 Reactivity: Human, Mouse, Rat WB, IHC, FACS, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Alternative Name
- CD184 / CXCR4 (CXCR4 Products)
- Background
- C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R
- Gene ID
- 7852
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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