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ICAM2 antibody

ICAM2 Reactivity: Human FACS, IP, IHC (fro) Host: Mouse Monoclonal CBR-IC2-2 unconjugated
Catalog No. ABIN2967162
  • Target See all ICAM2 Antibodies
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Reactivity
    • 63
    • 25
    • 20
    Human
    Host
    • 53
    • 13
    • 13
    Mouse
    Clonality
    • 54
    • 24
    Monoclonal
    Conjugate
    • 39
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM2 antibody is un-conjugated
    Application
    • 47
    • 46
    • 25
    • 19
    • 17
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human CD102 cDNA transfected COS cells
    Clone
    CBR-IC2-2
    Isotype
    IgG2a
    Top Product
    Discover our top product ICAM2 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 2-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Alternative Name
    CD102 / ICAM-2 (ICAM2 Products)
    Synonyms
    ICAM2 antibody, CD102 antibody, Icam-2 antibody, Ly-60 antibody, intercellular adhesion molecule 2 antibody, LOC506088 antibody, ICAM2 antibody, LOC616254 antibody, LOC100140873 antibody, Icam2 antibody
    Background
    Intercellular adhesion molecule 2,CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.,ICAM2
    Gene ID
    3384
    UniProt
    P13598
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