Proteoglycan 3 antibody (AA 170-185)

Catalog No. ABIN289531

Product Details anti-Proteoglycan 3 Antibody

Target: Proteoglycan 3 (PRG3)

Binding Specificity: AA 170-185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Proteoglycan 3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogen shares 87 % sequence identity with the Mouse homolog.

Purification: Affinity chromatography purified

Immunogen: PRG3 antibody was raised in rabbit using AA 170-185 [VTLIHSQVALADKELL] of the 41 kDa human PRG3 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Proteoglycan 3

Target: Proteoglycan 3 (PRG3)

Alternative Name: PRG3 (PRG3 Products)

Synonyms: MBP2 antibody, MBPH antibody, proteoglycan 3, pro eosinophil major basic protein 2 antibody, proteoglycan 3 antibody, PRG3 antibody, Prg3 antibody

Background: The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF.