ESR2 antibody

Catalog No. ABIN289423

Product Details anti-ESR2 Antibody

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Gel Shift (GS)

Specificity: The immunogen for this antibody is completely conserved in human and marmoset ERB protein.

Cross-Reactivity: Human, Mouse (Murine), Primate, Rat (Rattus), Sheep (Ovine)

Purification: Affinity chromatography purified

Immunogen: Estrogen receptor beta antibody was raised in rabbit using a synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat estrogen receptor beta as the immunogen.

Isotype: IgG

Application Details

Application Notes: Gel Shift: 1-5 µL, ICC: 2-4 µg/mL, IF: 0.5 µg/mL, IHC-F: 1-2 µg/mL, IHC-P: 1-2 µg/mL WB: 1-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 1 mg/mL BSA and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Alternative Name: Estrogen Receptor beta (ESR2 Products)

Synonyms: ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody

Background: Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific geneactivation through direct interaction with estrogen response elements (ERE's).

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling