DRD3 antibody
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- Target See all DRD3 Antibodies
- DRD3 (Dopamine Receptor D3 (DRD3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DRD3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity (Details)
- This human D3R peptide showed no significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). It is 94 % conserved in monkey, 72 % with mouse and 68 % with rat D3R receptors.
- Purification
- Affinity chromatography purified
- Immunogen
- Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.
- Isotype
- IgG
- Top Product
- Discover our top product DRD3 Primary Antibody
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- Application Notes
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ELISA: 0.5-1 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Affinity purified IgG lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- DRD3 (Dopamine Receptor D3 (DRD3))
- Alternative Name
- Dopamine D3 Receptor (DRD3 Products)
- Synonyms
- DRD3 antibody, D3R antibody, D3DR antibody, ETM1 antibody, FET1 antibody, dopamine receptor D3 antibody, drd3 antibody, DRD3 antibody, Drd3 antibody
- Background
- Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
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