PP5 antibody (FITC)
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- Target See all PP5 (PPP5C) Antibodies
- PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PP5 antibody is conjugated to FITC
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~58 kDa.
- Cross-Reactivity
- Human
- Purification
- Protein G Purified
- Immunogen
- Full length human PP5 protein
- Clone
- 12F7
- Isotype
- IgG1
- Top Product
- Discover our top product PPP5C Primary Antibody
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2868712 was sufficient for detection of PP5 in 15 μg of human A431 lysates by ECL analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
- Alternative Name
- PP5 (PPP5C Products)
- Background
- Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, potentially playing a role in the regulation of cell growth and differentiation. PP5 or PPT is predominantly a nuclear protein and interacts with CDC16 and CDC27. It is found in association with several proteins that influence intracellular signlaing-cascades intitiated by hormones (glucocorticoids) or cellular stress (hypoxia, oxidative stress and DNA Damage). It phosphorylates serine residues of skeletal muscle phosphorylase and histone H1. It may also be involved in mitosis and RNA biogenesis regulation (1,2).
- Gene ID
- 5536
- NCBI Accession
- NP_006238
- UniProt
- P53041
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