HYOU1 antibody (PerCP)
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- Target See all HYOU1 Antibodies
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HYOU1 antibody is conjugated to PerCP
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~170 kDa.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Recombinant Full length GRP170 Protein
- Clone
- 6E3-2C3
- Isotype
- IgG2b
- Top Product
- Discover our top product HYOU1 Primary Antibody
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anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibody
HYOU1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibodyHYOU1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibodyHYOU1 Reactivity: Human, Rat WB, IHC, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 274-303) antibodyHYOU1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB18634 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 1-140) antibodyHYOU1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (HRP)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 HRP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (FITC)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 FITC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Atto 390)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 Atto 390
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2868643 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
- Alternative Name
- GRP170 (HYOU1 Products)
- Background
- GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
- Gene ID
- 10525
- NCBI Accession
- NP_006389
- UniProt
- Q9Y4L1
- Pathways
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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