Prostate Specific Antigen antibody (C-Term)

Catalog No. ABIN2857041

Product Details anti-Prostate Specific Antigen Antibody

Target: Prostate Specific Antigen (PSA)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to PSA (kallikrein-related peptidase 3)
PSA antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PSA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: kallikrein related peptidase 3 (PSA Products)

Synonyms: APS antibody, KLK2A1 antibody, PSA antibody, hK3 antibody, KLK3 antibody, Klk1c10l2 antibody, RSGK-50 antibody, RSKG-50 antibody, rGK-3 antibody, Kal-3 antibody, Kal3 antibody, Klk3 antibody, AAP-S antibody, MP100 antibody, Psa antibody, R74825 antibody, goku antibody, kallikrein related peptidase 3 antibody, kallikrein 3 antibody, kallikrein 1-related peptidase C3 antibody, kallikrein B, plasma 1 antibody, aminopeptidase puromycin sensitive antibody, KLK3 antibody, Klk1c3 antibody, Klkb1 antibody, Npepps antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Cellular Localization: Secreted

Molecular Weight: 29 kDa

Gene ID: 354

UniProt: P07288

Pathways: Complement System