ABR antibody (C-Term)

Catalog No. ABIN2857024

Product Details anti-ABR Antibody

Target: ABR (Active BCR-Related (ABR))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABR antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Rat (Rattus), Pig (Porcine), Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Pig (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to ABR (active BCR-related gene)
ABR antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ABR. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: A431 , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ABR

Target: ABR (Active BCR-Related (ABR))

Alternative Name: ABR (ABR Products)

Synonyms: MDB antibody, xabr antibody, 6330400K15Rik antibody, AU042359 antibody, active BCR-related antibody, active BCR-related L homeolog antibody, active BCR-related gene antibody, ABR antibody, abr.L antibody, Abr antibody

Background: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.

Molecular Weight: 98 kDa

Gene ID: 29

Pathways: Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity