Leukotriene B4 Receptor/BLT antibody

Catalog No. ABIN2857016

Product Details anti-Leukotriene B4 Receptor/BLT Antibody

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leukotriene B4 Receptor/BLT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to P2Y7 (leukotriene B4 receptor)
P2Y7 antibody [N3C2], Internal

Purification: Affinity purified by Protein A.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Leukotriene B4 Receptor. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Leukotriene B4 Receptor/BLT

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Alternative Name: leukotriene B4 receptor (LTB4R Products)

Synonyms: BLT1 antibody, BLTR antibody, CMKRL1 antibody, GPR16 antibody, LTB4R1 antibody, LTBR1 antibody, P2RY7 antibody, P2Y7 antibody, Ltb4r1 antibody, LTB4R antibody, lt4r1 antibody, Ltb4r antibody, mBLTR antibody, leukotriene B4 receptor antibody, leukotriene B4 receptor-like antibody, Leukotriene B4 receptor 1 antibody, leukotriene B4 receptor 1 antibody, LTB4R antibody, Ltb4r antibody, LOC415617 antibody, lt4r1 antibody, Ltb4r1 antibody

Background: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molecular Weight: 38 kDa

Gene ID: 1241

UniProt: Q15722