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GRPR antibody

GRPR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2857015
  • Target See all GRPR Antibodies
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Reactivity
    • 42
    • 14
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 1
    • 1
    Rabbit
    Clonality
    • 43
    • 1
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRPR antibody is un-conjugated
    Application
    • 19
    • 17
    • 14
    • 8
    • 8
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit polyclonal antibody to GRPR (gastrin-releasing peptide receptor)
    GRPR antibody [C1C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GRPR. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product GRPR Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLaS3 , Molt-4 , mouse pancreas , mouse brain , rat brain , rat pancreas

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Alternative Name
    gastrin releasing peptide receptor (GRPR Products)
    Synonyms
    GRPR antibody, GRP-R antibody, gastrin releasing peptide receptor antibody, GRPR antibody, Grpr antibody
    Background
    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

    Cellular Localization: Cell membrane, Multi-pass membrane protein
    Molecular Weight
    43 kDa
    Gene ID
    2925
    UniProt
    P30550
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