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Ugt1 antibody

UGT1A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856950
  • Target See all Ugt1 (UGT1A) products
    Ugt1 (UGT1A) (UDP Glucuronosyltransferase 1 Family, Polypeptide A Complex Locus (UGT1A))
    Reactivity
    • 1
    • 1
    • 1
    Human
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This Ugt1 antibody is un-conjugated
    Application
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to UGT1A (UDP glucuronosyltransferase 1 family, polypeptide A)
    UGT1A antibody [C1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human UGT1A. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse liver , 293T , A431 , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.47 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Landerer, Kalthoff, Paulusch, Strassburg: "UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice." in: Cancer science, Vol. 111, Issue 11, pp. 4266-4275, (2020) (PubMed).

    Zahreddine, Culjkovic-Kraljacic, Gasiorek, Duchaine, Borden: "GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs." in: ACS chemical biology, Vol. 14, Issue 3, pp. 348-355, (2019) (PubMed).

  • Target
    Ugt1 (UGT1A) (UDP Glucuronosyltransferase 1 Family, Polypeptide A Complex Locus (UGT1A))
    Alternative Name
    UGT1A (UGT1A Products)
    Synonyms
    Ugt1a3 antibody, zgc:123097 antibody, zgc:66393 antibody, UDP glucuronosyltransferase 1 family a, b antibody, ugt1ab antibody
    Gene ID
    54600
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