ASPA antibody

Catalog No. ABIN2856897

Product Details anti-ASPA Antibody

Target: ASPA (Aspartoacylase (ASPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASPA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Monkey, Mouse

Characteristics: Rabbit Polyclonal antibody to Aspartoacylase (aspartoacylase (Canavan disease))
Aspartoacylase antibody [N1C3-2]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Aspartoacylase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: ASPA-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.33 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-ASPA antibody (ABIN2856897)

Huber, Hofer, Trefely, Pelzmann, Madreiter-Sokolowski, Duta-Mare, Schlager, Trausinger, Stryeck, Graier, Kolb, Magnes, Snyder, Prokesch, Kratky, Madl, Wellen, Bogner-Strauss: "N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1866, Issue 3, pp. 337-348, (2019) (PubMed).

Target Details for ASPA

Target: ASPA (Aspartoacylase (ASPA))

Alternative Name: aspartoacylase (ASPA Products)

Synonyms: asp antibody, acy2 antibody, ACY-2 antibody, ASP antibody, ACY2 antibody, Acy-2 antibody, Acy2 antibody, nur7 antibody, zgc:171507 antibody, aspartoacylase antibody, Aspartoacylase antibody, ASPA antibody, aspa antibody, Fbal_2465 antibody, Aspa antibody

Molecular Weight: 36 kDa

Gene ID: 443

UniProt: P45381