PDE1A antibody
PDE1A
Reactivity: Human
IHC (p), WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target See all PDE1A products
- PDE1A (Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
-
Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)
PDE1A antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PDE1A. The exact sequence is proprietary.
- Isotype
- IgG
-
- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
-
Positive Control: H1299 , HeLa , mouse brain , rat brain
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.74 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- PDE1A (Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
- Alternative Name
- phosphodiesterase 1A (PDE1A Products)
- Synonyms
- CAM-PDE-1A antibody, HCAM-1 antibody, HCAM1 antibody, HSPDE1A antibody, phosphodiesterase 1A antibody, PDE1A antibody
- Background
-
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]
- Molecular Weight
- 61 kDa
- Gene ID
- 5136
- UniProt
- P54750
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