PEX19 antibody

Catalog No. ABIN2856772

Product Details anti-PEX19 Antibody

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX19 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to PEX19 (peroxisomal biogenesis factor 19)
PEX19 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PEX19. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse liver , PC-12 , Rat-2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.01 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Alternative Name: peroxisomal biogenesis factor 19 (PEX19 Products)

Synonyms: BEST:GH03076 antibody, CG5325 antibody, DmelPex19 antibody, Dmel\\CG5325 antibody, D1S2223E antibody, HK33 antibody, PBD12A antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody, Pxf antibody, PxF antibody, Peroxin-19 antibody, Peroxin 19 antibody, Peroxisomal farnesylated protein antibody, peroxisomal biogenesis factor 19 antibody, Pex19 antibody, Bm1_19905 antibody, PEX19 antibody

Background: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).

Cellular Localization: Cytoplasm , Peroxisome membrane, Lipid-anchor, Cytoplasmic side

Molecular Weight: 33 kDa

Gene ID: 5824

UniProt: P40855