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SENP2 antibody (N-Term)

SENP2 Reactivity: Human WB, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856760
  • Target See all SENP2 Antibodies
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Binding Specificity
    • 15
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 38
    • 32
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 47
    • 7
    Rabbit
    Clonality
    • 47
    • 7
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SENP2 antibody is un-conjugated
    Application
    • 44
    • 19
    • 17
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Cow (Bovine)
    Cross-Reactivity (Details)
    Bovine (88 %)
    Characteristics
    Rabbit Polyclonal antibody to SENP2 (sentrin-specific protease 2)
    SENP2 antibody [N1], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SENP2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product SENP2 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: 293T , Molt-4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhou, Zheng, Hu, Wang, Zhang, Zou, Zhong, Wang, Wu, Kang: "SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).

  • Target
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Alternative Name
    SENP2 (SENP2 Products)
    Synonyms
    2310007L05Rik antibody, 4930538C18Rik antibody, AI646780 antibody, AW554757 antibody, Smt3ip2 antibody, SuPr-1 antibody, mKIAA1331 antibody, AXAM2 antibody, SMT3IP2 antibody, Axam antibody, SUMO/sentrin specific peptidase 2 antibody, SUMO1/sentrin/SMT3 specific peptidase 2 antibody, Sumo1/sentrin/SMT3 specific peptidase 2 antibody, Senp2 antibody, SENP2 antibody
    Background
    SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM]

    Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side , Cytoplasm
    Molecular Weight
    68 kDa
    Gene ID
    59343
    Pathways
    Chromatin Binding
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