MAGEA11 antibody (N-Term)

Catalog No. ABIN2856757

Product Details anti-MAGEA11 Antibody

Target: MAGEA11 (Melanoma Antigen Family A, 11 (MAGEA11))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: Rabbit polyclonal antibody to MAGEA11 (melanoma antigen family A, 11)
MAGEA11 antibody [N2N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MAGEA11. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: A431 , H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MAGEA11

Target: MAGEA11 (Melanoma Antigen Family A, 11 (MAGEA11))

Alternative Name: MAGEA11 (MAGEA11 Products)

Synonyms: MAGEA11 antibody, CT1.11 antibody, MAGE-11 antibody, MAGE11 antibody, MAGEA-11 antibody, melanoma antigen family A, 11 antibody, MAGE family member A11 antibody, Magea11 antibody, MAGEA11 antibody

Background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Nucleus , Cytoplasm

Molecular Weight: 48 kDa

Gene ID: 4110