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GALNS antibody (Center)

GALNS Reactivity: Human, Mouse, Rat WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856743
  • Target See all GALNS Antibodies
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Binding Specificity
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    Human, Mouse, Rat
    Host
    • 54
    • 2
    • 1
    Rabbit
    Clonality
    • 57
    Polyclonal
    Conjugate
    • 21
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GALNS antibody is un-conjugated
    Application
    • 43
    • 25
    • 19
    • 15
    • 13
    • 13
    • 13
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Characteristics
    Rabbit Polyclonal antibody to GALNS (galactosamine (N-acetyl)-6-sulfate sulfatase)
    GALNS antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human GALNS. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: H1299 , Neuro2A , C2C12 , PC-12 , Rat2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Alternative Name
    GALNS (GALNS Products)
    Synonyms
    GALNAC6S antibody, GAS antibody, GalN6S antibody, MPS4A antibody, mFLJ00319 antibody, galns antibody, zgc:158385 antibody, galactosamine (N-acetyl)-6-sulfatase antibody, galactosamine (N-acetyl)-6-sulfate sulfatase antibody, N-acetylgalactosamine-6-sulfatase antibody, galactosamine (N-acetyl)-6-sulfatase L homeolog antibody, GALNS antibody, Galns antibody, Celly_0425 antibody, galns.L antibody, galns antibody
    Background
    This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

    Cellular Localization: Lysosome
    Molecular Weight
    58 kDa
    Gene ID
    2588
    Pathways
    Glycosaminoglycan Metabolic Process
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