PIGR antibody

Catalog No. ABIN2856741

Product Details anti-PIGR Antibody

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGR antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to PIGR (polymeric immunoglobulin receptor)
PIGR antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PIGR. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.39 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PIGR

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Alternative Name: polymeric immunoglobulin receptor (PIGR Products)

Synonyms: DKFZp469G1013 antibody, RNPIGR2 antibody, pIgA-R antibody, polymeric immunoglobulin receptor antibody, PIGR antibody, Pigr antibody

Background: The poly-Ig receptor is expressed on several glandular epithelia including those of liver and breast. It mediates transcellular transport of polymeric immunoglobulin molecules. It is a member of the immunoglobulin superfamily (Hood et al., 1985 [PubMed 3917857]). The receptor has 5 units with homology to the variable (V) units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions.[supplied by OMIM]

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Secretory component: Secreted

Molecular Weight: 83 kDa

Gene ID: 5284

UniProt: P01833