XPNPEP2 antibody (Center)

Catalog No. ABIN2856725

Product Details anti-XPNPEP2 Antibody

Target: XPNPEP2 (X-Prolyl Aminopeptidase (Aminopeptidase P) 2, Membrane-Bound (XPNPEP2))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPNPEP2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Pig (Porcine), Rat (Rattus), Cow (Bovine)

Cross-Reactivity (Details): Mouse (89 %), Pig (90 %), Rat (89 %), Bovine (89 %)

Characteristics: Rabbit polyclonal antibody to XPNPEP2 (X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound)
XPNPEP2 antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human XPNPEP2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A549 , HeLa , HepG2 , HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-XPNPEP2 antibody (ABIN2856725)

Wei, Jiang, Lv, Tan, Wang, Zhou, Cheng, Gao, Chen, Wang, Zou, Li, Ma, Hu, Ma, Luo, Xi: "TMTP1-modified Indocyanine Green-loaded Polymeric Micelles for Targeted Imaging of Cervical Cancer and Metastasis Sentinel Lymph Node in vivo." in: Theranostics, Vol. 9, Issue 24, pp. 7325-7344, (2020) (PubMed).

Li, Dai, Xu, Huang, Zhou, Luo, Ma, Xi, Lv, Ma: "XPNPEP2 is associated with lymph node metastasis in prostate cancer patients." in: Scientific reports, Vol. 9, Issue 1, pp. 10078, (2019) (PubMed).

Target Details for XPNPEP2

Target: XPNPEP2 (X-Prolyl Aminopeptidase (Aminopeptidase P) 2, Membrane-Bound (XPNPEP2))

Alternative Name: XPNPEP2 (XPNPEP2 Products)

Synonyms: APP2 antibody, 9030008G12Rik antibody, mAPP antibody, XPNPEP2 antibody, zK61O11.1 antibody, zgc:63528 antibody, X-prolyl aminopeptidase 2 antibody, X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound antibody, X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound L homeolog antibody, XPNPEP2 antibody, Xpnpep2 antibody, xpnpep2.L antibody, xpnpep2 antibody

Background: Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes.

Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor

Molecular Weight: 76 kDa

Gene ID: 7512