FMO2 antibody

Catalog No. ABIN2856714

Product Details anti-FMO2 Antibody

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to FMO2 (flavin containing monooxygenase 2 (non-functional))
FMO2 antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FMO2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FMO2

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Alternative Name: flavin containing monooxygenase 2 (FMO2 Products)

Synonyms: FMO 1B1 antibody, FMO 2 antibody, FMO1B1 antibody, 2310008D08Rik antibody, 2310042I22Rik antibody, AW107733 antibody, MGC68715 antibody, FMO4 antibody, FMO2 antibody, flavin containing monooxygenase 2 antibody, flavin containing monooxygenase 2 L homeolog antibody, FMO2 antibody, Fmo2 antibody, fmo2.L antibody

Background: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

Cellular Localization: Microsome membrane , Endoplasmic reticulum membrane

Molecular Weight: 54 kDa

Gene ID: 2327

UniProt: Q99518