TUBA1A antibody

Catalog No. ABIN2856707

Product Details anti-TUBA1A Antibody

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Drosophila melanogaster, Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to alpha Tubulin 1A (tubulin, alpha 1a)
alpha Tubulin 1A antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human alpha Tubulin 1A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NIH-3T3 , mouse brain , Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-TUBA1A antibody (ABIN2856707)

Chiu, Wen, Wang, Hsu, Tsai, Hung, Tseng, Shyr: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).

Target Details for TUBA1A

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Alternative Name: tubulin alpha 1a (Tuba1a Products)

Synonyms: Tuba1 antibody, B-ALPHA-1 antibody, LIS3 antibody, TUBA3 antibody, Tuba-1 antibody, TUBA3D antibody, TUBA3E antibody, wu:fb37a10 antibody, 1t antibody, ALPHA 84C antibody, Alpha-Tubulin84B antibody, BEST:LD32507 antibody, CG1913 antibody, DM1alpha antibody, DTA1 antibody, Dmel\CG1913 antibody, T antibody, TBA1_DROME antibody, Talpha1 antibody, Tub antibody, Tub 84B antibody, Tub1C antibody, Tuba84B antibody, Tubalpha1 antibody, a-tub84B antibody, a1t antibody, aTub84B antibody, alpha-Tub antibody, alpha-Tub84B antibody, alpha-tub antibody, alpha-tub84B antibody, alpha-tubulin antibody, alpha-tubulin 84B antibody, alpha1 antibody, alpha1t antibody, alpha1tub antibody, alpha1tub84B antibody, alpha84B antibody, alphaT antibody, alphaTUB antibody, alphaTUB84B antibody, alphaTub antibody, alphaTub1 antibody, alphaTub84 antibody, alphat-1 antibody, alphatub antibody, alphatub84B antibody, anon-EST:Liang-1.59 antibody, anon-EST:Liang-2.30 antibody, chr3R:2914276..2914416 antibody, clone 1.59 antibody, clone 2.30 antibody, l(3)84Bd antibody, l(3)g3 antibody, ms(3)nc33 antibody, nc33 antibody, tub antibody, tubA84B antibody, tubalpha1 antibody, tubulin antibody, TUBA1A antibody, Tuba1a antibody, Tuba2 antibody, alphatub84 antibody, b-alpha-1 antibody, lis3 antibody, tuba1a antibody, tuba1a-a antibody, tuba1a-b antibody, tuba3 antibody, tubulin, alpha 1A antibody, tubulin alpha 1a antibody, tubulin, alpha 1a antibody, tubulin alpha-1B chain antibody, tubulin alpha-1A chain antibody, tubulin alpha-3 chain-like antibody, alpha-Tubulin at 84B antibody, tubulin alpha 1a L homeolog antibody, Tuba1a antibody, TUBA1A antibody, LOC608147 antibody, LOC100392817 antibody, LOC425049 antibody, tuba1a antibody, alphaTub84B antibody, LOC100051840 antibody, LOC100340483 antibody, LOC100726777 antibody, tuba1a.L antibody

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Molecular Weight: 50 kDa

Gene ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase