GSTT1 antibody

Catalog No. ABIN2856663

Product Details anti-GSTT1 Antibody

Target: GSTT1 (Glutathione S-Transferase theta 1 (GSTT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to GSTT1 (glutathione S-transferase theta 1)
GSTT1 antibody

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Full length human GSTT1 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: rat liver

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-GSTT1 antibody (ABIN2856663)

Zhou, Kim, Chong, Tan, Amin, Sadat Badieyan, Mukherjee, Ghazizadeh, Zeng, Guo, Crespo, Zhang, Kenyon, Robinson, Apostolou, Wang, Xiang, Evans, Studer, Chen: "A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival." in: Nature communications, Vol. 9, Issue 1, pp. 4815, (2018) (PubMed).

Target Details for GSTT1

Target: GSTT1 (Glutathione S-Transferase theta 1 (GSTT1))

Alternative Name: glutathione S-transferase theta 1 (GSTT1 Products)

Background: Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55 % amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Cellular Localization: Cytoplasm

Molecular Weight: 27 kDa

Gene ID: 2952

UniProt: P30711