HMGCL antibody (full length)

Catalog No. ABIN2856650

Product Details anti-HMGCL Antibody

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Binding Specificity: full length

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Characteristics: Rabbit Polyclonal antibody to HMGCL (3-hydroxymethyl-3-methylglutaryl-CoA lyase)
HMGCL antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human HMGCL Recombinant protein.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: H1299 , mouse liver , rat liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HMGCL

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Alternative Name: HMGCL (HMGCL Products)

Synonyms: Afu7g01720 antibody, AO090038000541 antibody, AW476067 antibody, HL antibody, zgc:56248 antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase antibody, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase antibody, hmgcl.S antibody, HMGCL antibody, AFUA_7G01720 antibody, NFIA_114450 antibody, ACLA_065820 antibody, AOR_1_910074 antibody, PMAA_004600 antibody, TSTA_103060 antibody, ARB_04874 antibody, TRV_06573 antibody, Hmgcl antibody, hmgcl antibody

Background: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Mitochondrion matrix

Molecular Weight: 34 kDa

Gene ID: 3155