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CD70 antibody (C-Term)

CD70 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856605
  • Target See all CD70 Antibodies
    CD70 (CD70 Molecule (CD70))
    Binding Specificity
    • 9
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 95
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 62
    • 32
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 63
    • 38
    • 1
    Polyclonal
    Conjugate
    • 51
    • 11
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD70 antibody is un-conjugated
    Application
    • 52
    • 44
    • 44
    • 40
    • 21
    • 19
    • 17
    • 14
    • 11
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to CD27L (CD27L (CD70)) (CD27L (CD70) molecule)
    CD70 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD70. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CD70 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Jurkat

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CD70 (CD70 Molecule (CD70))
    Alternative Name
    CD70 molecule (CD70 Products)
    Synonyms
    CD27LG antibody, Cd27l antibody, Tnfsf7 antibody, CD27L antibody, TNFSF7 antibody, CD70 antigen antibody, CD70 molecule antibody, Cd70 molecule antibody, Cd70 antibody, CD70 antibody
    Background
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Cellular Localization: Membrane
    Molecular Weight
    21 kDa
    Gene ID
    970
    UniProt
    P32970
    Pathways
    Cancer Immune Checkpoints
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