Amylin/DAP antibody

Catalog No. ABIN285658

Product Details anti-Amylin/DAP Antibody

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivity: Human, Rat, Cat, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amylin/DAP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Immunogen: Amylin antibody was raised in rabbit using amylin as the immunogen.

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in distilled water, and dilute further in 0.1 M PBS with 1 % BSA and 0.1 % Sodium Azide.

Concentration: Lot specific

Buffer: Lyophilized undiluted rabbit serum.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details for Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Alternative Name: Amylin (IAPP Products)

Synonyms: DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody

Background: Amylin or islet amyloid polypeptide (IAPP) is produced in the pancreas beta cells and coreleased with insulin. The amino acid sequence shows great homology with CGRP. Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.

Pathways: Hormone Activity, Feeding Behaviour